Noted Publications:

• Thanassi, D.G., Saulino, E.T., Lombardo, M.-J., Roth, R., Heuser, J., and Hultgren, S.J. (1998) The PapC usher forms an oligomeric channel: implications for pilus biogenesis across the outer membrane. Proc. Natl. Acad Sci USA. 95:3146-3151.
• Saulino, E.T., Thanassi, D.G., Pinkner, J.S., and Hultgren, S.J. (1998) Ramifications of kinetic partitioning on usher-mediated pilus biogenesis. EMBO J.17:2177-2185.
• Thanassi, D.G., Saulino, E.T., and Hultgren, S.J. (1998) The chaperone/usher pathway: a major terminal branch of the general secretory pathway.Curr. Opinion Microbiol.1:223-231.
• Thanassi, D.G. and Hultgren, S.J.(2000) Multiple pathways allow protein secretion across the bacterial outer membrane. Curr. Opin. Cell Biology 12:420-430
• Thanassi DG, Stathopoulos C, Dodson K, Geiger D, Hultgren SJ (2002) Bacterial outer membrane ushers contain distinct targeting and assembly domains for pilus biogenesis. J Bacteriol 2002, 184:6260-6269.
• Gil H, Benach JL, Thanassi DG: Presence of pili on the surface of Francisella tularensis. Infect Immun 2004, 72:3042-3047.
• Ng TW, Akman L, Osisami M, Thanassi DG (2004) The usher N terminus is the initial targeting site for chaperone-subunit complexes and participates in subsequent pilus biogenesis events. J Bacteriol, 186:5321­5331.
• Li H, Qian L, Chen Z, Thahbot D, Liu G, Liu T, Thanassi DG. (2004) The outer membrane usher forms a twin-pore secretion complex. J Mol Biol, 344:1397-1407.
• Henderson NS, Shu Kin So S, Martin C, Kulkarni R, Thanassi DG (2004) Topology of the outer membrane usher PapC determined by site-directed fluorescence labeling. J Biol Chem, 279: 53747-53754.
• Thanassi DG, Stathopoulos C, Karkal A, Li H. (2005) Protein secretion in the absence of ATP: the autotransporter, two-partner secretion and chaperone/usher pathways of gram-negative bacteria (review). Mol Membr Biol. Jan-Apr;22(1-2):63-72. Review.
• Kostakioti M, Newman CL, Thanassi DG, Stathopoulos C. (2005) Mechanisms of protein export across the bacterial outer membrane.J Bacteriol. Jul;187(13):4306-14. Review.
• So SS, Thanassi DG. (2006) Analysis of the requirements for pilus biogenesis at the outer membrane usher and the function of the usher C-terminus. Mol Microbiol. Apr;60(2):364-75.
• Gil H, Platz GJ, Forestal CA, Monfett M, Bakshi CS, Sellati TJ, Furie MB, Benach JL, Thanassi DG. (2006) Deletion of TolC orthologs in Francisella tularensis identifies roles in multidrug resistance and virulence. Proc Natl Acad Sci U S A. Aug 22;103(34):12897-902.