Noted Publications:

• Andersen, JS., VanScoy, S, Cheng, T-F,  Gomez, D and Reich, NC.  2008. IRF-3-dependent and augmented target genes during viral infection. Genes and Immunity, 9:168-175.
• Iyer, J and Reich, NC.  2008. Constitutive Nuclear Import of Latent and Activated STAT5a by its Coiled Coil Domain, FASEB J., 22:391-40.
• Reich NC, Liu L. 2006. Tracking STAT nuclear traffic. Nat Rev Immunol. Aug;6(8):602-12.
• Cheng TF, Brzostek S, Ando O, Van Scoy S, Kumar KP, Reich NC. 2006. Differential activation of IFN regulatory factor (IRF)-3 and IRF-5 transcription factors during viral infection. J Immunol. Jun 15;176(12):7462-70.
• Liu L, Gao Y, Qiu H, Miller WT, Poli V, Reich NC. 2006. Identification of STAT3 as a specific substrate of breast tumor kinase. Oncogene. Aug 10;25(35):4904-12.
• Gilbert, M.M., B.K. Weaver, and N.C. Reich. 2005. A novel functional activator of the Drosophila JAK/STAT pathway, unpaired2, is revealed by an in vivo reporter of pathway activation. Mech Development, 122: 939-948.
• Liu, L., K. McBride, and N.C. Reich. 2005. STAT3 import is independent of tyrosine phosphorylation and mediated by importin-a3, Proc Natl Acad Sci USA, 102:8150-8155.
• Banninger, G. and N.C. Reich 2004. STAT2 nuclear trafficking. J. Biol. Chem.. 279: 39199-206.
• Gomez, D. and N.C. Reich, 2003. Stimulation of Primary Human Endothelial Cell Proliferation by IFN-alpha, J. Immunology 170: 5373-5381
• McBride, K., G. Banninger, C. McDonald and N.C. Reich. 2002. Regulated nuclear import of the STAT1 transcription factor by direct binding to importin-a5, EMBO J., in press
• Faruqi. T.R., D. Gomez, X. Bustelo, D. Bar-Sagi and N.C. Reich. 2001. Rac1 mediates STAT3 activation by autocrine IL-6. Proc Natl Acad Sci USA, 98:9014-9019
• Weaver, B., O. Ando, K.P. Kumar and N.C. Reich. 2001. Apoptosis promoted by the dsRNA activated factor (DRAF1) during viral infection independent of the action of interferon or p53. FASEB J., 15:501-551
• McBride, K.E., C. McDonald, and N.C. Reich. 2000. Nuclear export signal located within the DNA-binding domain of the STAT1 transcription factor. EMBO J. 19:6196-6206.
• Kumar, K.P., K. McBride, B. Weaver, C. Dingwall, and N.C. Reich. 2000. Regulated nuclear-cytoplasmic localization of interferon regulatory factor-3 subunit of the dsRNA activated transcription factor, DRAF1. Mol. & Cell. Biol. 20:4159-4168.
• McDonald, C. and N.C. Reich. 1999. Cooperation of the transcriptional coactivators CBP/p300 with STAT6. J. Interferon & Cytokine Res. 19:711-722.
• Weaver, B.K., K.P. Kumar and N.C. Reich. 1998. Interferon Regulatory Factor 3 and CREB-Binding Protein/p300 are Subunits of the dsRNA Activated Transcription Factor, DRAF1. Mol. & Cell. Biology 18:359-368.
• Martinez-Moczygemba, M., M.J. Gutch, D. French and N.C. Reich. 1997. Distinct STAT Structure Promotes Interaction of STAT2 with the p48 Subunit of the Interferon-a Stimulated Transcription Factor, ISGF3. J. Biol. Chem. 272:200070-200076.
• Kotanides, H. and N.C. Reich. 1996. Interleukin-4 Induced STAT6 Recognizes and Activates a Target Site in the Promoter of the Interleukin-4 Receptor Gene. J. Biol. Chem. 271:25555-25561.
• Gilmour, K.C., R. Pine and N.C. Reich. 1995. Interleukin-2 Activates STAT5 (Mammary Gland Factor) and Specific Gene Expression in T Lymphocytes. Proc. Natl. Acad. Sci. USA 92:10772-10776. 
• Daly, C. and N.C. Reich. 1995. Characterization of dsRNA Activated Factors (DRAFs) as Positive Regulators of Interferon-a Stimulated Genes. J. Biol. Chem. 270:23739-23746. 
• Gilmour, K.C. and N.C. Reich. 1994. Receptor to Nucleus Signaling by Prolactin and Interleukin-2 Via Activation of Latent DNA-Binding Factors. Proc. Natl. Acad. Sci. USA 91:6850-6854. 
• Kotanides, H. and N.C. Reich. 1993. Tyrosine Phosphorylation is Required for Rapid Activation of a DNA-Binding Factor by Interleukin-4. Science 262:1265-1267. 
• Gutch, M.J., C. Daly, and N.C. Reich. 1992. Tyrosine Phosphorylation is Required for Activation of an a-Interferon Stimulated Transcription Factor. Proc. Natl. Acad. Sci. USA 89:11411-11415.
• Reich, N.C., B. Evans, D. Levy, D. Fahey, E. Knight, Jr, and J.E. Darnell, Jr. 1987. Interferon-induced transcription of a gene encoding a 15kDa protein depends on an upstream enhancer element. Proc. Natl. Acad. Sci. USA 84:6394-6398.
• Reich, N.C. and A.J. Levine. 1984. Growth regulation of a cellular tumor antigen, p53, in non-transformed cells. Nature 308:199-201.