| Courses | Mentors |
| First year students may rotate in up to four different laboratories of their choice during the first year of study (Experimental Microbiology, HBM 509/510). At the end of the first year, students join a laboratory to conduct their dissertation research. |
First Year |
| Fall Semester |
| - HBM 503 - Molecular Genetics |
Introduces the classical work and current developments in lower and higher genetic systems. Covers gene structure and regulation in prokaryotic and eukaryotic organisms, mutational analysis and mapping, transposable elements, and biological DNA transfer mechanisms. Bacteriophage as well as lower and higher eukaryotic systems are used to illustrate aspects of molecular genetic structure and function.
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| - MCB 520 - Graduate Biochemistry I |
Several topics in modern biochemistry are treated at an advanced level. Topics covered will include protein structure, enzyme kinetics and mechanisms, and enzyme regulation.
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| - HBM 509 - Experimental Microbiology (laboratory rotations) |
| An introduction to modern microbiological research. The selection of laboritories is made in consultation with the student's advisory committee. By taking part in ongoing projects the student will learn experimental produres and techniques and become acquainted with research opportunities in the department. |
| - MCB 517 - Biomembranes |
| Examines the molecular architecture of membranes; the organization, functions, and assembly of lipids and proteins in biological membranes. |
| - HBM 690 - Microbiology Student Seminar |
A weekly meeting devoted to current work in the department. Enrolled students present seminars each week throughout the term.
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| - BSB 515 - Computational Methods in Biochemistry and Structural Biology |
| Computational methods used in sequence searching and analysis. bioinformatics, graphical analysis of proteins and nucleic acids.
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| Spring Semester |
| - MCB 656 - Cell Biology |
| Introduction to the structural and functional organization of cells and tissues and to the way structure relates to function. Particular emphasis is placed on nuclear and chromosomal structure, signal transduction, protein translocation, the cytoskeleton and the extracellular matrix. The interaction of cellular structures and components and their regulation is stressed as is the organization and interaction of cells in tissues. The course is comparative and includes examples of cells and tissues from vertebrates, invertebrates, plants, and prokaryotic systems. |
|
| - HBM 692- Experimental Methods in Molecular Genetics and Microbiology |
| Students are introduced to the theory behind a variety of experimental methods used in modern molecular genetics laboratories through a series of formal lectures given by faculty in the Molecular Genetics and Microbiology Graduate Program as well as faculty from other biomedical graduate programs at Stony Brook University, Journal club-style classes alternate with these lectures in which the applications of these experimental methods are explored through discussions of papers from the literature. |
| - HBM 510- Experimental Microbiology |
| An introduction to modern microbiological research. The selection of laboratories is made in consultation with the student's advisory committee. By taking part in ongoing projects the student will learn experimental procedures and techniques and become acquainted with research opportunities in the department. |
| - HBM 690 - Microbiology Student Seminar |
| A weekly meeting devoted to current work in the department. Enrolled students present seminars each week throughout the term. |
| - GRD 500 - Integrity in Science |
| This course is designed to introduce students to the major issues in the ethics of science and research. Using a combination of readings - written and web-based - videos, lectures, case discussion and other exercises, students will investigate the moral values intrinsic to science and the professional and social values with which scientists must comply. Each class will begin with an introductory lecture followed by discipline-based, small group discussions designed and managed by faculty from the department or program from which the graduate students come. |
| - HBM 522 - Biology of Cancer |
A short course with the emphasis on cancer as a disease of man. Lectures address human cancer as seen by the clinician and as basic research relates to human diseasew. This course provides students with a link between courses in cell and molecular biology and the application of this basic information to tumor management.
- Offered every other year. |
Second Year |
| Fall Semester |
| - HBM 640 - Molecular Mechanisms of Microbial Pathogenesis |
This course covers the molecular mechanisms of pathogenesis of a selected group of very important viral and bacterial pathogens. While much of the course is taught by MGM faculty, a significant portion of the material is presented by invited lecturers who are leaders in their fields. Rather than present a "bug parade," the course focuses on principles of microbial pathogenesis as illustrated by the best understood viral and bacterial pathogens. This course is directed to graduate students, pot-doctorate and medical fellows, and advanced ,medical students who are contemplatibg careers in infectious disease research.
|
| - HBP 533 - Immunology |
Principles of immunology for graduate students in the biological sciences, including definition of antigens and antibodies, specificity of the immune response, immunoglobulin structure, the genetics of immunoglobulin synthesis, cellular cooperation in the immune response, hypersensitivity, tolerance immunogenetics.
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| - HBM 599 - Graduate Research |
Original investigations under faculty supervision.
|
| - HBM 690 - Microbiology Student Seminar |
| A weekly meeting devoted to current work in the department. Enrolled students present seminars each week throughout the term. |
| - HBM 691- Readings in Microbiology Literature |
| Readings in microbiology literature covering areas of molecular biology and genetics. |
| Spring Semester |
| - HBM 522 - Biology of Cancer |
A short course with the emphasis on cancer as a disease of man. Lectures address human cancer as seen by the clinician and as basic research relates to human diseasew. This course provides students with a link between courses in cell and molecular biology and the application of this basic information to tumor management.
- Offered every other year. |
| - HBM 599 - Graduate Research |
Original investigations under faculty supervision.
|
| - HBM 690 - Microbiology Student Seminar |
| A weekly meeting devoted to current work in the department. Enrolled students present seminars each week throughout the term. |
Advancement to Candidacy
After successfully completing all required courses, students take a written comprehensive examination that covers course material presented during the first three semesters of study. By the end of the fifth semester, students are expected to write and defend orally before a preliminary examination committee a proposal for their dissertation research. When these two examinations are successfully completed, a student is advanced to candidacy for the Ph.D. degree. |
Third Year and on (before advancement to candidacy:) |
| - HBM 599 - Graduate Research |
Original investigations under faculty supervision.
|
| - HBM 690 - Microbiology Student Seminar |
| A weekly meeting devoted to current work in the department. Enrolled students present seminars each week throughout the term. |
| Years 3 and on (after advancement to candidacy): |
| - HBM 699 - Dissertation Research in Microbiology |
| For the student who has advanced to candidacy. Original research will be under the supervision of the dissertation advisor and advisory committee. |
| - HBM 690 - Microbiology Student Seminar |
| A weekly meeting devoted to current work in the department. Enrolled students present seminars each week throughout the term. |
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